RESUMO
This study evaluated the efficacy of licorice bioadhesive hydrogel patches to control the pain and reduce the healing time of recurrent aphthous ulcer.This study was carried out in three episodes of ulcers: in the first episode of ulcer, all 15 patients were asked to record their baseline individual pain level by a visual analog scale. In the second and third episodes, comparative and consecutive subjective and objective evaluations of the bioadhesive were done. The effects of the following variables were investigated: (1) VAS pain score for 5 consecutive days, (2) profile of aphthous ulcers on days 3 and 5, (3) time to complete relief of pain and healing of the ulcers, (4) diameter of the lesions and necrotic zone.A significant reduction in VAS was recorded following application of the licorice patches on days 2, 3, 4 and 5 compared with the no-treatment group (p < 0.001). Licorice patches caused a significant reduction in the diameter of the inflammatory halo and necrotic center compared with the placebo group (p = 0.03).According to the results of this study, licorice bioadhesive can be effective in the reduction of pain and of the inflammatory halo and necrotic center of aphthous ulcers.
Assuntos
Adesivos/uso terapêutico , Glycyrrhiza/química , Hidrogel de Polietilenoglicol-Dimetacrilato/uso terapêutico , Fitoterapia , Estomatite Aftosa/tratamento farmacológico , Adulto , Feminino , Humanos , Masculino , Prevenção Secundária , Resultado do Tratamento , Adulto JovemRESUMO
A study in Babol, Islamic Republic of Iran, used a questionnaire to gather information on knowledge about oral cancer and its risk factors and to evaluate the efficacy of an educational brochure. From a community sample of 400 people, 76.0% had no knowledge of oral cancer. Mean knowledge score before the education intervention was 1.47 (standard deviation 3.40) out of 10. Knowledge about oral cancer was not associated with age, sex or education level but urban residents had better knowledge than rural residents. Mean knowledge score improved significantly by 5.92 (SD 3.30) at 1 month after the intervention among the 226 respondents who had read the brochure.
Assuntos
Educação em Saúde/métodos , Conhecimentos, Atitudes e Prática em Saúde , Neoplasias Bucais , Folhetos , Materiais de Ensino , Adolescente , Adulto , Idoso , Idoso de 80 Anos ou mais , Atitude Frente a Saúde , Estudos Transversais , Avaliação Educacional , Feminino , Humanos , Irã (Geográfico)/epidemiologia , Masculino , Pessoa de Meia-Idade , Neoplasias Bucais/diagnóstico , Neoplasias Bucais/epidemiologia , Neoplasias Bucais/etiologia , Características de Residência , Fatores de Risco , Estatísticas não Paramétricas , Inquéritos e Questionários , Materiais de Ensino/normasRESUMO
A study in Babol, Islamic Republic of Iran, used a questionnaire to gather information on knowledge about oral cancer and its risk factors and to evaluate the efficacy of an educational brochure. From a community sample of 400 people, 76.0% had no knowledge of oral cancer. Mean knowledge score before the education intervention was 1.47 [standard deviation 3.40] out of 10. Knowledge about oral cancer was not associated with age, sex or education level but urban residents had better knowledge than rural residents. Mean knowledge score improved significantly by 5.92 [SD 3.30] at 1 month after the intervention among the 226 respondents who had read the brochure
